• Interestingly the response of F del

  2018-11-13

  

  Interestingly, the response of F508del/Y1092X cells is almost double to that of F508del/G542X. While difference could be due to intrinsic responses of the F508del natriuretic peptide receptor from each of these donors, it is also plausible that the Y1092X mutation, given its localization towards the

• The genetic diversity and population structure of the specie

  2018-11-13

  

  The genetic diversity and population structure of the species have been elucidated by the use of two related methods, multilocus enzyme electrophoresis (MLEE) starting in the early 1980s and multilocus sequencing typing (MLST) at the end of the 1990s (Caugant et al., 1986a; Maiden et al., 1998). Bot

• The generation of autoantibodies to TAAs is not fully

  2018-11-13

  

  The generation of autoantibodies to TAAs is not fully understood. TAA proteins are most likely either mutated, overexpressed, post-translationally modified, misfolded, aberrantly cleaved, or aberrantly localized in tumor order URB597 (Casiano et al., 2006). It has been reported that HSP60 localize

• Treatment of acquired TTP involves plasma exchange PEX to pr

  2018-11-13

  

  Treatment of acquired TTP involves plasma exchange (PEX) to provide a new source of ADAMTS13. Steroids are used to target the autoimmune component of the disease. Therapy with rituximab reduces rates of recurrence (Scully et al., 2011; Westwood et al., 2013). Recombinant ADAMTS13 is currently underg

• Although it is currently unclear if DNA methylation changes

  2018-11-13

  

  Although it is currently unclear if DNA methylation changes are the cause or the consequence of the disease, it is clear that DNA methylation changes occur early during disease pathogenesis and precede disease detection by histological and/or imaging methods. Several DNA methylation-based biomarkers

• br Case report A healthy

  2018-11-12

  

  Case report A healthy 17-year-old male presented to our clinic with multiple asymptomatic flesh-colored papules on his right palm for 5 years. On physical examination, several pinpoint-sized flesh-colored papules with central pitting and purpuric change located on his right palm were noted (Figur

• There are a large number

  2018-11-12

  

  There are a large number of reticulated pigmentations that need to be distinguished, including dyskeratosis congenita (DKC), X-linked reticulate pigmentary disorder (XLRPD), Naegeli-Franceschetti-Jadassohn syndrome (NFJS), dermatopathia pigmentosa reticularis (DPR), DDD, reticulate acropigmentation

• br Case Report A year old male patient presented

  2018-11-12

  

  Case Report A 40-year-old male patient presented with a complaint of excessive sweating on the right side of the face and the left side of the waist lasting 5 years. He had no prior traumatic event, pyretic disease, or stroke before these symptoms developed. Dermatological examination demonstrate

• Introduction Psoriasis is a chronic inflammatory disease aff

  2018-11-12

  

  Introduction Psoriasis is a chronic inflammatory disease affecting the skin and joints. The itch and pain caused by the skin and joint lesions affect patient quality of life. Moreover, the appearance of skin lesions often have negative impacts on patient psychological and social functions. A growin

• Ultimate tensile strength of SMMC B

  2018-11-12

  

  Ultimate tensile strength of SMMC B4C-160 μm is 527 Mpa. The above expressions are used to calculate the penetration depth of projectile intoTarget-1 A similar approach was adopted for evaluating the penetration depth in SMMC B4C-60 μm and SMMC-30μm, and the penetration depth of 40.5mmand 38.17 mm

• The product development task for this

  2018-11-12

  

  The product development task for this life-saving pyrotechnic product must be to get as much gas as possible in shortest possible time. Correct formula writing has now led us to a question that must have a rational answer, viz., why is the iron oxide there? A possible answer may be that it acts as a

• We are both delighted and excited that

  2018-11-12

  

  We are both delighted and excited that this is the second time has published scientific papers presented at an International Symposium on Ballistics (ISB). This particular issue publishes papers presented at the 29th ISB, co-chaired by Ian Cullis and Clive Woodley, QinetiQ, and supported by the Nati

• Prostaglandin E2 cost Introduction Health and appearance of

  2018-11-12

  

  Introduction Health and appearance of gingiva are important parts of a smile [1]. The color of the gingiva is various among different individuals and it is thought to be associated with cutaneous pigmentation [2]. It varies from light to dark brown or black. The skin tone, texture and color differ

• In Fig the authors categorize three types

  2018-11-12

  

  In Fig. 3, the authors categorize three types of variables that can lead to cooperation. Management (Management Variables) is a source of cooperation if managers share information with transparency. Unions, by being more responsive and integrating also lead to fostering cooperation. The unions in th

• br Introduction Over two decades

  2018-11-12

  

  Introduction Over two decades ago, the ideology of strategic management accounting (SMA) was introduced into the literature as a seminal development with Simmonds and Bromwich as lead academics. During this they say period, SMA came to prominence among other innovative techniques designed to res

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