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Pilsicainide might increase hERG proteins
2019-05-21
Pilsicainide might increase hERG proteins via facilitating the transcription of hERG from DNA to RNA or the translation of hERG RNA into hERG protein. Qualitative RT-PCR demonstrated the absence of an increase in hERG mRNA expression levels after pilsicainide treatment (Supplemental Fig. S2), indica
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Despertar de la ilusi n
2019-05-21
Despertar de la “ilusión” le significa hcv protease inhibitor Villoro su tránsito a la crítica de las filosofías de J. Rawls yJ. Habermas, afirma que no son pertinentes para el caso de nuestra condición social y política, ya que a pesar de las diferencias importantes entre sus teorías, ambas parten
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India is the second largest consumer and third largest
2019-05-21
India is the second largest consumer and third largest producer of tobacco in the world. The Indian Government has been significantly engaged in addressing the tobacco problem. A major policy, the Cigarettes and Other Tobacco Products Act (COTPA) was implemented in 2003, followed by WHO\'s Framework
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Human ether a go go related gene HERG encodes
2019-05-20
Human-ether-a-go-go-related gene (HERG) encodes the α-subunit of rapidly-activating delayed-rectifier potassium VE-822 that generate IKr. This outward potassium current is elicited during the plateau phase of action potentials and is required for repolarization [4]. After being translated in the end
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To assess quality independent from quantity Imamura and coll
2019-05-20
To assess quality independent from quantity, Imamura and colleagues assessed dietary intake adjusted for 2000 kcal per day. An unfortunate consequence of this adjustment is that the role of unrestrained energy intake in the obesity and diabetes epidemics seems to be rendered obsolete. For example, i
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Visto el franquismo como el gran eje de
2019-05-20
Visto el franquismo como el gran eje de la discordia, el punto de in flexión se produjo en 1949 con motivo de la presentación en la onu de una propuesta conjunta de cuatro países de América Latina: Brasil, Bolivia, Colombia y Perú. La propuesta de resolución del cuatripartito latinoamericano (proyec
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Ad Mapu lleg a convertirse en un
2019-05-20
Ad Mapu llegó MLN8237 convertirse en un gran referente que contribuyó al fortalecimiento de la conciencia de la situación mapuche, así lo explica Víctor Toledo al mencionar que es en este momento cuando aparece bosquejada la autodeterminación como propuesta del pueblo mapuche, y recuerda las palabra
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br Materials and methods br Results
2019-05-20
Materials and methods Results and discussion ABT-737 is a BH3-mimetic targeting Bcl-2, Bcl-XL and Bcl-W. The aim of the experiments was to test whether inhibition of Bcl-2 and Bcl-XL using ABT-737 can eradicate the CD34+/CD38− AML cell population. Bone marrow MNCs from patients (Table 1) were
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There is also a pressing need to change the
2019-05-20
There is also a pressing need to change the way societal and fgf receptor inhibitor progress is measured to more accurately reflect an ecosocial approach to health. We are thus interested in applying the Happy Planet Index (HPI) at a community as well as at a national level. The HPI, an innovative
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br Discussion A previous report demonstrated an
2019-05-20
Discussion A previous report demonstrated an adenosine-sensitive reentrant AT not involving an AV nodal pathway in the vicinity of the apex of Koch\'s triangle, which could be ablated at the earliest atrial activation site in the right supero-septal region [3]. Otomo et al. reported a “left-varia
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El n mero de que corresponde al segundo
2019-05-20
El número 63 de , que corresponde al segundo semestre del presente año 2016, pone prostaglandin receptor disposición de la comunidad académica un conjunto variado de artículos sobre América Latina y un pequeño dedicado a la literatura brasileña. Eduardo Ayala Tafoya abre el número con “Lope de Aguir
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Although a well experienced group reported
2019-05-18
Although a well experienced group reported a very high success rate of 80% after catheter ablation even in patients with congestive heart failure [40], the evidence described above suggests that catheter ablation alone is not sufficient to treat AF in patients with hemodynamic deterioration. This in
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The first variant in the non spine topic describes a
2019-05-18
The first variant in the non-spine topic describes a patient with an excellent performance status, a favorable life expectancy, and an asymptomatic withaferin a lesion which does not pose an obvious risk for pathologic fracture. While the authors acknowledge that research has begun to determine whe
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Cryotherapy related soft tissue injury usually occurs within
2019-05-18
Cryotherapy related soft tissue injury usually occurs within a few weeks postoperatively. Skin necrosis is a significant complication if freezing of the superficial surface occurs. Constant irrigation of the adjacent tissues with warm saline reduces the chance of skin necrosis. Our rate of infection
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br Results Compared to the respective untreated groups
2019-05-18
Results Compared to the respective untreated groups, the VT duration was shorter in clonidine-treated ETB-deficient rats during phase I and in wild-type rats during phase II (Fig. 1A). Heart rate (HR) increased in both untreated groups, but this response was blunted after clonidine, mainly in ETB
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