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Furthermore certain components in the Melanocyte Growth Medi
2019-07-02
Furthermore, certain components in the Melanocyte Growth Medium seem to influence the response to UV radiation [17]: UV-induced effects on tyrosinase activity were less distinct in melanocytes cultured with phorbol 12-myristate 13-acetate [18], which was also an ingredient in our Melanocyte Growth M
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Prostaglandin E receptor subtype EP is a transmembrane
2019-07-02
Prostaglandin E receptor subtype 4 (EP4) is a transmembrane G-coupled protein receptor activated by prostaglandin E2 (PGE2). EP4 activation exerts anti-inflammatory effects in adipose tissue by dampening the levels of inflammatory chemokines [12]. In the mouse, EP4 deficiency aggravates fragmentatio
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br Cytochrome P monooxygenases Cytochrome P monooxygenases P
2019-07-02
Cytochrome P450 monooxygenases Cytochrome P450 monooxygenases (P450s) belong to one of Nature’s most versatile group of enzymes for C–H functionalization and are able to perform challenging regioselective and stereoselective activations of remote, unactivated C(sp3)–H bonds, for which there are o
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saha hdac A study profiling chemokine expression in
2019-07-02
A study profiling chemokine expression in LCLs revealed high expression levels of CCR6, CCR7, and CCR10 and low expression of CXCR4 and CXCR5 in EBV immortalized cells. Accordingly, LCLs showed a markedly increase in migration in response to the ligands of CCR6 (CCL20), CC7 (CCL21), and CCR10 (CCL28
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Several TERRA binding proteins have also been
2019-07-01
Several TERRA-binding proteins have also been discovered, especially telomeric duplex DNA binding proteins TRF1 and TRF2, pointing to a significant role of TERRA in more general chromosome biology [14], [20], [21]. TRF2 is a key component of Shelterin that protect chromosome termini [22]. Telomeres
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br Sustained monomorphic ventricular tachycardia br Monomorp
2019-07-01
Sustained monomorphic ventricular tachycardia Monomorphic VT is defined as sustained when lasting longer than 30s or requires earlier intervention due to haemodynamic instability [89]. Most commonly, sustained MMVT occurs in the setting of diseased myocardium, but may also be idiopathic, occurr
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Since antithrombotic therapy for patients with AF is rapidly
2019-07-01
Since antithrombotic therapy for patients with AF is rapidly changing with the increasing use of dabigatran, rivaroxaban, and apixaban, some of the primary issues that will influence the future revision of various guidelines (HRS [Heart Rhythm Society], ESC [European Society of Cardiology], ACC [Ame
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The status of Fas and Fas ligand expression
2019-07-01
The status of Fas and Fas ligand expression can predict recurrence of hepatocellular carcinoma. These results suggest that the evaluation of Fas and Fas ligand expression potentially has a significant prognostic value for DFS of HCC patients, in addition to patient clinical stage, and can be regarde
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br Conclusions br Conflict of interest
2019-07-01
Conclusions Conflict of interest Introduction Gastrointestinal stromal tumor (GIST) arises from the mesenchymal tissue of the gastrointestinal tract. The annual incidence of this condition is 7 cases per million people in the West. However, the incidence could in fact be higher in Asian pop
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br La profesionalizaci n del poeta como un perfil creador
2019-07-01
La profesionalización del poeta como un perfil creador La oferta sin precedentes que se ha experimentado en el terreno poético luego de varias iniciativas editoriales públicas y privadas en los años 1980-2010 (por ejemplo, Gabriel Bernal Granados o León Plascencia Ñol: 235) ha generado una bonanz
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baicalein Performance based financing often highlighted
2019-07-01
Performance-based financing, often highlighted in Rwanda\'s story, has had mixed results when applied elsewhere, partly because of breakdowns in execution. For example, the failure of the performance-based financing initiative in neighbouring Uganda was caused by challenges in setting targets, deliv
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br Alegato y ret rica de la
2019-07-01
Alegato y retórica de la violencia en la Brevíssima relación de la destruyción de las Indias En el año 1552 fray Bartolomé de las Casas, en Sevilla, se ocupa de dar RG7388 la imprenta ocho de sus principales escritos, entre ellos la Brevíssima relación, compuesta diez años antes: “Y parecióle cos
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Otra cuesti n que debi afrontar la pol tica
2019-07-01
Otra cuestión que debió afrontar la política exterior argentina fue la necesidad de recuperar la inserción del país en Latinoamérica. En el abordaje de esta cuestión, como en la referida Physcion las situaciones de dependencia, la política exterior contó con un contexto internacional muy permisivo,
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Los principios de Promover intercambio
2019-07-01
Los principios de Promover intercambio de información junto con el de Mantener acuerdos y arreglos bilaterales y regionales son inseparables del principio de Cooperación y emergen de manera directa del mismo. El accionar de los estados miembros que conforman una organización interregional, consolida
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En este mapeo las revistas que se destacan
2019-07-01
En este mapeo, las revistas que se destacan son Polis, de la Universidad Bolivariana de Chile, con 28 trabajos que mencionan beta-Nicotinamide mononucleotide Morin, Educere, de la Universidad de los Andes de Venezuela, con 17 artículos que citan a Morin, y EccoS, de la Universidade Nove de Julho (un
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